Nevertheless, this group represents a category of patients, presumably with community-acquired infection, who could potentially be treated with narrower spectrum antibiotics when local ecology allows. Current guidelines for the selection of antibiotic therapy in critically ill patients do not mention length of stay in the hospital as a consideration for empirical treatment in patients with high-severity non-nosocomial infections. Microbiological isolates and antibiotic treatments were remarkably different between these groups with fewer carbapenems, glycopeptides and antifungals used in patients with shorter stays. The findings in this study suggest that physicians around the world seem to comply with international guidelines in this field as most patients receive broad-spectrum antibiotics, often in combination with agents aimed at fungi or even at resistant Gram-positive microorganisms. These pathogens may have a greater degree of pathogenicity although Stenotrophomonas is generally not considered to be a major pathogen, or may be more difficult to treat.Дetailed data regarding antibiotic resistance, including information regarding resistance to specific antibiotics, were not collected so we are unable to comment further on these aspects. Furthermore, there were important differences in microbiology between survivors and non-survivors, with P. Among the Gram-positive microorganisms, enterococci were most prevalent, whereas staphylococci were uncommon. In the patients with abdominal infections, the picture was substantially different: Gram-negative bacteria were isolated almost twice as frequently as Gram-positive bacteria, with E. The microbiology patterns were diverse, and quite different from those in the overall EPIC II study population, in which staphylococci were isolated most frequently, and Gram-positive and Gram-negative organisms were equally present.

Most notably, the impact of cirrhosis was considerable with a 2.ДЄ recent analysis of the Project Impact database also showed that cirrhosis was independently associated with an increased risk of day mortality.

As expected, comorbidities, such as cirrhosis and hematological cancer, were associated with increased mortality, as was found in the EPIC II patients in general. Finally, the large number of concomitant infections may also have affected outcomes.

In addition, abdominal infections are typically polymicrobial and often associated with resistant organisms in the current study, non-survivors more frequently had P. ДЇailed source control is often difficult to identify and can be a cause of persistent infection. First, timely source control is particularly important in the management of abdominal infections, and the method by which source control is obtained may influence outcomes. The higher mortality rate in patients with abdominal infections in our study may be explained by a number of differences between abdominal and other infections.

Mortality in patients who had abdominal infections was significantly higher than in patients who had other infections most of which were respiratory infections, which was not found in previous studies. The severity of disease and presence of comorbidities determined outcome in these patients. Microbiology patterns and antibiotic treatments were diverse in this group of patients, and pathogens were different in patients who had been in the ICU for a longer period of time than in those more recently admitted. The results show that abdominal infections are associated with significant mortality rates and that concomitant infections are frequent. This study is one of the first to look at abdominal infections in critically ill patients from a global perspective. Candida species were isolated in patients Almost all the patients with abdominal infections Overall ICU and hospital mortality rates were Survivors and non-survivors had similar patterns of infecting organisms, except for P. вЂЋOkCupid: Online Dating App on the App StoreДЄntibiotic resistance was relatively rare: ampicillin-resistant enterococci were isolated in 70 patients 7.

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